Awesome help in reading Pap results

When I went to the OB on Monday I asked for a copy of my test results.  I want to see them. I want to hold them and look at them.  It makes me feel more in control and not so in the dark.   But reading them can be hard.  Check out this site.  It really lists what I needed to know.  You can google terms not on here.  If you find a more detailed or better site let me know.  I copy and pasted what I found below and the link is on top.

http://www.estronaut.com/a/pap_smear_results_interpretation.htm

Abnormal Pap Smears — Reading Your Results

More after the break

The Bethesda System

The Betheseda is the third major reworking of the the Pap smear classification system, since the test’s inception in 1941. It has been around for about 10 years and is the most common system used. How a woman’s test is classified is important as it will determine what happens next. There are many levels of abnormal results. The majority are NOT cancer. Some are downright benign. Frequently, low end abnormalities will go away on their own. Still, all abnormalities could progress to cancer, so it is very important to do any follow-up tests or procedures to prevent this. While all the aspects of the results have guidelines attached to them, this is still a judgement call on the part of the reader. She looks at the slide and decides how the slide matches up against the classification criteria.

Pre-cancerous cells are called Cervical Intraepithelial Neoplasms (C.I.N.). They are classified I (1) through III (3). Doctors often call these “CIN 1” and so on. The more abnormal the cells and therefore closer to cancer they are, the higher the number. The CIN levels are determined by colposcopy and/or biopsy which are the follow-up tests for abnormal Paps.

Part I — Statement of Adequacy

This has nothing to do with you, so don’t worry. It is the lab’s assessment of how good the sample was by the time it arrived on their end. If the clinician does not pick up enough cells in all the different areas, if the sample is not fixed quickly enough, or if it is damaged in transit, the results might be inferior. However, keep in mind that with the rise in lawsuits against labs for missing cervical cancers, they are very quick to label a sample as unsatisfactory. The possible results are :

1. “satisfactory” This is a sample with cells from each of the areas clearly defined — the outer cervix, the inner cervix, and the vaginal wall.

2. Satisfactory, but limited by ______. The pathologists will state the reason for the limits. What is done will be up to the primary care doctor.

3. Unsatisfactory. Lubricants, excessive discharge, blood, inflammation, too few endocervical cells are possible reasons. The test should be repeated if there are too few endocervical cells. Although many labs state this result when their hurried slide readers simply don’t see them right away. A cytobrush sampling can improve this too. A course of antibiotics should be used before repeating the slides marred by inflammation. If blood and inflammation cannot be cleared enough to get a readable sample, then doctor will skip ahead to more advanced testing.

Part II — A General Categorization — A Statement of Normal vs. Abnormal

This is the part that makes us nervous. It is a general statement as to the normalcy or lack thereof of the sample. There are three possible results:

1. Within normal limits This is the result every woman wants. There’s no next step other than to have another pap at whatever yearly interval she and her provider have decided on.

2. Benign Cellular Changes. These are abnormalities that do not progress to cancer. Infections and/or inflammation is the most common cause. Antibiotics and repeat exam is the most likely outcome here.

3. Epithelial Cell Abnormality These are the results that make us worry. These are not always cancer and not all will lead to cancer, but they can.

Benign Cellular Changes — Details

Infection — These are common sexually transmitted and non-sexually transmitted infrections. If they are suseptible to antibiotics, then the woman will be treated.

Trichomonas vaginalis — this is sexually transmitted and the woman’s partner will have to be treated as well .

Fungal organisms morphologically consistent with Candida ssp. This is yeast.

Predominance of coccibacilli consistent with Actinomyces ssp.

Cellular changes associated with herpes simplex virus– this is sexually transmitted, but not curable.

Other

Reactive and reparative changes — these may be due to gyny procedures or childbirth related.

Inflamation (includes typical repair) — the woman may be re-tested. Even if none of the definitive signs of infection above is present, her doctor may treat her with antibiotics, especially if the inflammatory result is persistent.

Atrophy with inflamation (“atrophic vaginitis”) This is usually seen in post-menopausal women. Hormone replacement, vaginal estrogen creasm, or lubricants may be suggested.

Radiation

Intrauterine contraceptive device (IUD)

Other

Epithelial Changes — Details

Squamous Cell

Atypical squamous cells of undetermined significance (ASCUS) — the most common type of abnormal result. It is not cancer. It is often due to infection or irritation. Many times these resolve on their own. Most women will be re-tested in a few months. High risk women will have colposcopy right away.

Squamous intraepithelial lesion (SIL)

Low-grade squamous intraepithelial lesion (LSIL)– A woman with these result will usually have a colposcopy within 4 weeks. It is not yet cancer. Encompassing: cellular changes associated with human papillomavirus

Mild dysplasia (cervical intraepithelial neoplasia [CIN]-I)

High-grade squamous intraepithelial lesion (HSIL) — a woman will usually have a colposcopy right away. This is not yet cancer. Encompassing: Moderate dysplasia (CIN-II) –not cancer

Severe dysplasia and carsinoma in situ (CIN-III) — this is cancer, but limited to the cervix and still has an excellent chance of cure.

Squamous cell carcinoma

Glandular Cell

Presence of unexpected endometrial cells — these are from the uterine lining.

Atypical glandular cells of undetermined significance(AGCUS) — It could indicate cervical or endometrial problems (due to cells from the uterine lining being picked up on the Pap). This is handled the sometimes with endocervical curettage and endometrial biopsy.

Endocervical adenocarcinoma

Endometrial adenocarcinoma

Other Adenocarcinoma

Other

Hormonal evaluation — lastly there will be a hormonal evaluation. This means do the cells appear as they typically would for a reproductive age vs. menopausal age woman. These are done off the vaginal wall sample of the Pap.

Hormonal pattern compatible with age and history

Hormonal pattern incompatible with age and history

specify — depending on the specification, the doctor may do further testing for hormonal problems

Hormonal evaluation not possible due to:

specify — if this results occurs, it is usually not necessary to re-do the test, as this is not the essential reason for the Pap.

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December 7, 2007. Tags: , , , , , . Doc Appointments, HPV, information, Test Results.

3 Comments

  1. Mary, cervical cancer survivor replied:

    Another site you’ll find really helpful is http://www.TheHPVTest.com. Lots of great information on HPV and how to deal with it, as well as people’s personal stories and what they’re doing to cope with their diagnosis.

    I am an 11-year cervical cancer survivor who had abnormal paps for about a year before they finally diagnosed “adenocarcinoma in situ” of the cervix (contained early stage). Following my diagnosis I had a hysterectomy but didn’t need radiation or chemo because they caught it early, which is why annual paps and asking for the HPV Test along with your Pap is so so important. And if your doc says you don’t need it, ask for it anyway, and say that you want a “baseline” measurement for the future.

    I’m proof that people do survive and that HPV can go into remission, which means that it is “subclinical” and won’t show up as active on an HPV test. However, under stress the virus can become active again, so regular HPV testing is important for anyone who has tested HPV positive in their past even if they’ve had a subsequent negative HPV test as I did just last month.

    You’re so wise to stay informed and to share your research with your doctor. They are often so busy with so many issues, that internet-informed patients become their teachers, even if they don’t admit it. 🙂

    It’s been hard for me to admit that I’ve had an STD, and…I know that sharing my story could someone’s life. Your’s will too.

    You’re brave, you’re strong, and you care. That’s angel work. Thank you.

  2. Lynn replied:

    My Pap results say simply……
    Epithelial cell abnormality 1
    There are atypical endometrial cells present 2
    Please tell me what this means!!
    God Bless,Lynn Sanderson

  3. Lynn replied:

    Why are theyso non specific….Im absolutely terrified The doctors put me on sedatives but i want to know what it all means! Please help Regards Lynn

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